Tissue Healing in Space
Tissue Healing in Space

Partner - Life Sciences - ITALY

Fabio Celotti

Contact :

Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano (Milano, Italy)

phone:  +39 2 50318208

email:  Fabio.celotti@unimi.it  

Website:  www.disfeb.unimi.it/



Graduated "summa cum laude" in Medicine at the University of Milano, 1974, specialized in Clinical Endocrinology at the University of Florence,1977. Associated professor of Endocrinology and General pathology (1987-93), now full professor of General pathology at the University of Milano. Director of the Department of Endocrinology, Pathophysiology and Applied Biology of the University of Milano and Chairmen of The Course of Pharmacy of the University of Milano (2009-2012). Dean of the Faculty of Pharmacological Sciences of the University of Milano (2015-2018). Member of the ELGRA Management Comity (2015-2017).During his research activity, he has collaborated in several national and/or International research projects. He is author of more than 150 publications in national and international journals and editor or co-editor of several scientific books


One of the research topic of prof. Celotti’s lab is the study of cell migration in wound and fracture healing. His studies have been focused on 1) the identification of the platelet growth factors present in platelet rich plasma (PRP) preparations and involved in migration and proliferation of osteoblasts and 2) in the characterization of the cytoskeletal apparatus involved in cellular movements and in its modulation by PRP. Studies on cell motility in simulated μg using the Rotating Cell Culture System (RCCS) were recently realized in collaboration with Dr. Monica Monici, with particular regard to PRP effects on microgravity induced alterations related to wound healing.


Dr. Celotti’s expertise ranges from the preparation, maintenance and propagation of cell cultures of different animal species to the main techniques for molecular biology studies. In detail, it is focused on:

-proliferation and migration studies in “in vitro” cell systems

- mRNA and protein level evaluation by means of Real-Time PCR and western blotting to analyse the expression levels of different proteins/molecules

- analysis of cytoskeletal markers by immunofluorescence and confocal microscopy

- preparation and characterization of platelet rich plasma


Available equipment and techniques:

The Department of Pharmacological and Biomolecular Sciences (Università degli Studi di Milano) is fully equipped for studies in molecular and cell biology:

1)      BioHazard Laminar flow cabinets, CO2 incubators and any tool for cell cultures

2)      Microscopy (4 Zeiss light and inverted phase microscopes) and confocal (Zeiss LSM510) microscopy facilities

3)      Enspire MultiMode Plate Reader for luminescence and fluorescence assays;

4)      ChemiDoc Gel-imaging system for western blot analysis

5)      Cell transfection systems

6)      PCR and quantitative real-time PCR machines for advanced studies in molecular biology

7)      Omics analysis;

8)      Microgravity



Universita Milano_Celotti.jpg