Tissue Healing in Space
Tissue Healing in Space


Monica Monici

Contact :   ASAcampus Joint Laboratory, ASA Res. Div, Dept. of Experimental and Clinical Biomedical Sciences, University of Florence  phone:   +39 055 2758366   email:    monica.monici@unifi.it    Website:  https://www.graphene.cam.ac.uk

Contact :

ASAcampus Joint Laboratory, ASA Res. Div, Dept. of Experimental and Clinical Biomedical Sciences, University of Florence

phone:  +39 055 2758366

email:  monica.monici@unifi.it

Website: https://www.graphene.cam.ac.uk



Actual Position: Scientific Research Manager of ASA Res. Div. ASA srl. Scientific Resp. for industry at ASAcampus Joint Laboratory, ASA Res. Div. - Dept. of Experimental and Clinical Biomedical Sciences, University of Florence. From 2017, Coordinator of the Life Sciences Activities in the ESA- European Space Agency - Topical Team on “Tissue Healing in Space: Techniques for promoting and monitoring tissue repair and regeneration”. From 2016, Partner in the project CORM “The Coenzyme Q10 (CoQ10) as antiapoptotic countermeasure for retinal lesions induced by radiation and microgravity on the International Space Station (ISS): experiment on cultured retinal cells”. The project was supported by ASI – the Italian Space Agency. The in flight experiment was  launched   with SPX-12 on 14th August 2017 and performed on the ISS during the mission VITA, with the participation of the Italian astronaut Paolo Nespoli.  2015-17, President of ELGRA (European Low Gravity Research Association). From 2015, PI project “SUTURE – Wound Healing and Sutures in Unloading Conditions” approved by ESA – European Space Agency.  2015, Founder partner of Probiomedica s.r.l., Spin off of the Univ. of Florence. 2014-2017, PI project “RITMI – Tissue repair in microgravity” founded by ASI -  Italian Space Agency. 2013-17, Member Management Committee ISSBB (Italian Society for Space Biomed. and Biotechnol.).  From 2009, Member Editorial Board of the “Italian Journal of Aerospace Medicine”. 2009, Co-inventor, Patent: WO2011055395, EP2496306, PCT/IT2009/000499, "Ingestible capsule for the treatment of gastric infections and particularly for the treatment of infections by H. Pylori”. From 2007, Executive Editor of the scientific journal “Energy for Health”.

From 2006 Member Management Committee AIMAS (Italian Ass. Aerospace Medicine). 2006 Founder partner of Biosuma s.r.l., Biosurfaces and Materials, Spin off of the Univ. of Siena.  2001-06, Researcher, person in charge of Biopto Div.,CLAM, CEO - Center of Excellence in Optronics. 1996, Co-inventor in the Patent: PCT/EP96/03201, "Fluorogenic substrates susceptible of fluorescence emission and photosensitization activity upon enzyme transformation suitable for diagnosis and photodynamic treatment of tumors". 1993-2000, Contract Researcher at Inst. Quant. Electr., CNR, and CEO - Center of Excellence in Optronics, Florence. 1990-92, Research fellowship, I. A. O., Ministry for Foreign Affairs, Florence. 1990, Photobiology School, European Society for Photobiology, Italian Society for Photobiology and University of  Sassari. 1989, Visiting Scientist at  Centre Etudes Nucléaires Saclay, France. 1989, School on Cellular and Molecular Bioengineering, CNR - National Research Council and University of Padua. 1987, First European School on Biomaterials, Euroxy (Commission of the European Communities, 3 Medical Programme), E.C. and University of Siena.1984, Nato Advanced Study Institute Primary Photo-Processes in Biology and Medicine, University of Padua.1982, Member Professional Registry of Italian Biologists. 1981, Course on Introduction to Industrial Biotechnology, University of Rome. 1980/82  Training at the University of Florence, Dept. of Chemistry, Florence, Italy. 1980, Degree in Biological Sciences.

Author of more than 100 publications: papers in scientific journals, book chapters, book editing.


  • Effect of physical stimuli (hypogravity, hypergravity, mechanical stimuli, light, electromagnetic fields) on cell behaviour and tissue homeostasis
  • Cellular and molecular mechanisms underlying the effects of physical therapies (laser, electric and magnetic fields) in physiatrics, rehabilitation and sport medicine
  • Application of optoelectronic techniques for research and diagnostics in biomedicine
  • Strategies to promote tissue repair
  • Fibroblasts and extracellular matrix


  • Space and gravitational biology
  • Photobiology
  • Cell biology
  • Cell differentiation
  • Stem cells
  • Fluorescence and autofluorescence microscopy and spectroscopy
  • Wound healing, tissue repair and regeneration

Available equipment and techniques:

Fully equipped laboratory for mammalian cell cultures and chemical preparation; fully equipped laboratory for photobiology, epifluorescence microscope, autofluorescence and immuno-fluorescence spectroscopy and microscopy + 3D imaging and microincubator coupled with fluorescence microscope; microplate readers for absorbance and transmittance; high power pulsed Nd:YAG laser, red and IR diode lasers; electromagnetic field sources; hyperfuge (3-18K, Sigma Zentrifugen); multi-sample centrifuge; RCCS-Rotating Cell Culture System.